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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Intermediate conductance calcium-activated potassium channel protein 4' and Ligand = 'BDBM50019902'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Intermediate conductance calcium-activated potassium channel protein 4


(Homo sapiens (Human))
BDBM50019902
PNG
(CHEMBL3287207)
Show SMILES CC(N1c2sccc2S(=O)(=O)CC1=O)c1ccc(F)c(OC(F)(F)F)c1
Show InChI InChI=1S/C15H11F4NO4S2/c1-8(9-2-3-10(16)11(6-9)24-15(17,18)19)20-13(21)7-26(22,23)12-4-5-25-14(12)20/h2-6,8H,7H2,1H3
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PC cid
PC sid
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Article
PubMed
n/an/a 39n/an/an/an/an/an/a



Temple University School of Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of human KCa3.1 overexpressed in HEK293 cells assessed as thallium influx preincubated for 15 mins followed by thallium/ionomycin addition...


ACS Med Chem Lett 5: 460-1 (2014)


Article DOI: 10.1021/ml500090s
BindingDB Entry DOI: 10.7270/Q2RJ4M2T
More data for this
Ligand-Target Pair