Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Interstitial collagenase' and Ligand = 'BDBM50109630'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50109630 ((3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-y...) Show SMILES COc1ccc(cc1)P(=O)(OC)N1Cc2ccccc2CC1C(=O)NO Show InChI InChI=1S/C18H21N2O5P/c1-24-15-7-9-16(10-8-15)26(23,25-2)20-12-14-6-4-3-5-13(14)11-17(20)18(21)19-22/h3-10,17,22H,11-12H2,1-2H3,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Organon K.K. Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloprotease-1 (MMP-1)(recombinant human collagenase-1).				J Med Chem 45: 919-29 (2002) BindingDB Entry DOI: 10.7270/Q2XK8G9Q
					More data for this Ligand-Target Pair