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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Isoprenylcysteine carboxyl methyltransferase' and Ligand = 'BDBM50384450'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Isoprenylcysteine carboxyl methyltransferase


(Homo sapiens (Human))
BDBM50384450
PNG
(CHEMBL2035531)
Show SMILES COC(=O)CCSC\C=C(/C)CCn1cc(CCc2cccc(c2)-c2ccccc2)nn1
Show InChI InChI=1S/C26H31N3O2S/c1-21(14-17-32-18-15-26(30)31-2)13-16-29-20-25(27-28-29)12-11-22-7-6-10-24(19-22)23-8-4-3-5-9-23/h3-10,14,19-20H,11-13,15-18H2,1-2H3/b21-14+
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.90E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of ICMT in cell free system


ACS Med Chem Lett 3: 15-19 (2012)


Article DOI: 10.1021/ml200106d
BindingDB Entry DOI: 10.7270/Q26T0NPK
More data for this
Ligand-Target Pair