Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
JAK3/JAK1 (Homo sapiens (Human)) | BDBM139694 (US8895544, 4) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of JAK1/JAK3 in human whole blood assessed as inhibition of IL-4 induced STAT6 phosphorylation preincubated for 45 mins followed by Il-4 a... | J Med Chem 60: 767-786 (2017) Article DOI: 10.1021/acs.jmedchem.6b01634 BindingDB Entry DOI: 10.7270/Q24J0HDZ | |||||||||||
More data for this Ligand-Target Pair |