BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50019484'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50019484 (CHEMBL384584 \| NH2-Tyr-D-Trp-Gly-Phe-Leu-Arg-Arg-D...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.0320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of [3H]-bremazocine binding to Opioid receptor kappa 1 in guinea pig cerebellum membrane homogenates.				J Med Chem 29: 1913-7 (1986) BindingDB Entry DOI: 10.7270/Q2Z89BCJ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50019484 (CHEMBL384584 \| NH2-Tyr-D-Trp-Gly-Phe-Leu-Arg-Arg-D...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for the agonistic activity against Opioid receptor kappa 1 in rabbit vas deferens.				J Med Chem 29: 1913-7 (1986) BindingDB Entry DOI: 10.7270/Q2Z89BCJ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair