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Found 1 hit Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50036137'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50036137
PNG
(2-[22-cyclopropylmethyl-2,16-dihydroxy-(2S,13R)-14...)
Show SMILES OC(=O)C[C@@H](NC(=O)c1cccc2c3C[C@@]4(O)C5Cc6ccc(O)c7O[C@@H](c3[nH]c12)C4(CCN5CC1CC1)c67)C(O)=O |TLB:16:15:38.19.18:33.31.32,24:38:15:33.31.32,34:33:15:38.19.18,THB:14:15:38.19.18:33.31.32|
Show InChI InChI=1S/C31H31N3O8/c35-20-7-6-15-10-21-31(41)12-18-16-2-1-3-17(28(38)32-19(29(39)40)11-22(36)37)24(16)33-25(18)27-30(31,23(15)26(20)42-27)8-9-34(21)13-14-4-5-14/h1-3,6-7,14,19,21,27,33,35,41H,4-5,8-13H2,(H,32,38)(H,36,37)(H,39,40)/t19-,21?,27+,30?,31-/m1/s1
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PC cid
PC sid
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Similars
PubMed
 893n/an/an/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
The opioid receptor affinity(Ki) was evaluated by competition with 9 (Opioid receptor kappa 1) on guinea pig brain membranes

J Med Chem 38: 402-7 (1995)


BindingDB Entry DOI: 10.7270/Q22N52W5
More data for this
Ligand-Target Pair