Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50068379 (5'-[N-(N'-Cyano)guanidinyl]-17-cyclopropylmethyl-6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Effect on binding affinity of mutational exchange of Glu297 in the Opioid receptor kappa 1 in transiently expressed rat cos-7 cells activity expresse... | J Med Chem 41: 4911-4 (1999) Article DOI: 10.1021/jm9805182 BindingDB Entry DOI: 10.7270/Q2K9387K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50068379 (5'-[N-(N'-Cyano)guanidinyl]-17-cyclopropylmethyl-6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Mutant factor against mu-[K303E] with Opioid receptor kappa 1 for binding affinity | J Med Chem 41: 4911-4 (1999) Article DOI: 10.1021/jm9805182 BindingDB Entry DOI: 10.7270/Q2K9387K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50068379 (5'-[N-(N'-Cyano)guanidinyl]-17-cyclopropylmethyl-6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Mutant factor of the compound against kappa[E297K] with Opioid receptor kappa 1 for binding affinity. | J Med Chem 41: 4911-4 (1999) Article DOI: 10.1021/jm9805182 BindingDB Entry DOI: 10.7270/Q2K9387K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50068379 (5'-[N-(N'-Cyano)guanidinyl]-17-cyclopropylmethyl-6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.46 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Binding affinity on HEK-293 cells transiently transfected with plasmids encoding the rat Opioid receptor kappa 1 | J Med Chem 43: 2759-69 (2000) BindingDB Entry DOI: 10.7270/Q2JD4W2W | |||||||||||
More data for this Ligand-Target Pair |