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Found 1 hit Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50088377'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50088377
PNG
(1-{2-[3-(3,4-Dichloro-phenyl)-2-oxo-tetrahydro-pyr...)
Show SMILES Clc1ccc(cc1Cl)N1CCCN([C@H](C[NH+]2CCCC2)c2ccccc2)C1=O
Show InChI InChI=1S/C22H25Cl2N3O/c23-19-10-9-18(15-20(19)24)26-13-6-14-27(22(26)28)21(16-25-11-4-5-12-25)17-7-2-1-3-8-17/h1-3,7-10,15,21H,4-6,11-14,16H2/p+1/t21-/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
PubMed
 0.420n/an/an/an/an/an/an/an/a



Universit£ di Napoli"Federico II"

Curated by ChEMBL


Assay Description
Inhibition of [3H]U-69593 binding to Opioid receptor kappa 1 in guinea pig brain homogenates

J Med Chem 43: 2124-34 (2000)


BindingDB Entry DOI: 10.7270/Q23N242D
More data for this
Ligand-Target Pair