Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50125464'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50125464 (1-(1-Phenyl-2-pyrrolidin-1-yl-ethyl)-3-p-tolylamin...) Show SMILES Cc1ccc(Nc2cccn(C(CN3CCCC3)c3ccccc3)c2=O)cc1 Show InChI InChI=1S/C24H27N3O/c1-19-11-13-21(14-12-19)25-22-10-7-17-27(24(22)28)23(18-26-15-5-6-16-26)20-8-3-2-4-9-20/h2-4,7-14,17,23,25H,5-6,15-16,18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Curated by ChEMBL					Assay Description Inhibition of [125I]-(D-Pro10)-Dynorphin A binding to human kappa opioid receptor from membranes of HEK293 cells				Bioorg Med Chem Lett 13: 1141-5 (2003) BindingDB Entry DOI: 10.7270/Q24J0DH2
					More data for this Ligand-Target Pair