Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50135805'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50135805 (17-{3-[4-hydroxy-(9R,10R)-17-azatetracyclo[7.5.3.0...) Show SMILES Oc1ccc2C[C@@H]3[C@@H]4CCCC[C@]4(CCN3CCCN3CC[C@]45CCCC[C@H]4[C@H]3Cc3ccc(O)cc53)c2c1 |TLB:18:19:27:36.30.29| Show InChI InChI=1S/C35H46N2O2/c38-26-10-8-24-20-32-28-6-1-3-12-34(28,30(24)22-26)14-18-36(32)16-5-17-37-19-15-35-13-4-2-7-29(35)33(37)21-25-9-11-27(39)23-31(25)35/h8-11,22-23,28-29,32-33,38-39H,1-7,12-21H2/t28-,29-,32+,33+,34+,35+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibitory activity against Opioid receptor kappa 1 in chinese Hamster Ovary (CHO) cell membranes was determined using [3H]U-69593 radioligand				J Med Chem 46: 5162-70 (2003) Article DOI: 10.1021/jm030139v BindingDB Entry DOI: 10.7270/Q2GX4C9C
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