Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50173258'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50173258 (1'-cyclooctylmethyl-1-cyclopropylmethyl-6-methoxys...) Show SMILES COc1ccc2c(c1)N(CC1CC1)C(=O)C21CCN(CC2CCCCCCC2)CC1 Show InChI InChI=1S/C26H38N2O2/c1-30-22-11-12-23-24(17-22)28(19-21-9-10-21)25(29)26(23)13-15-27(16-14-26)18-20-7-5-3-2-4-6-8-20/h11-12,17,20-21H,2-10,13-16,18-19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against human opioid receptor kappa 1 expressed in HEK293 cells using 3H-U69,593 radioligand				Bioorg Med Chem Lett 15: 5022-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.009 BindingDB Entry DOI: 10.7270/Q2RF5TKC
					More data for this Ligand-Target Pair