BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50205443'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50205443 (2-epi-2-thiosalvinorin A \| CHEMBL231537) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	151	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Displacement of [3H]U69,593 from rat cloned KOR				Bioorg Med Chem Lett 17: 2229-32 (2007) Article DOI: 10.1016/j.bmcl.2007.01.100 BindingDB Entry DOI: 10.7270/Q2MC8ZPK
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50205443 (2-epi-2-thiosalvinorin A \| CHEMBL231537) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	123	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Activity at human kappa opioid receptor expressed in HEK293 cells as intracellular calcium mobilization				Bioorg Med Chem Lett 17: 2229-32 (2007) Article DOI: 10.1016/j.bmcl.2007.01.100 BindingDB Entry DOI: 10.7270/Q2MC8ZPK
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair