Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50290974'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50290974 (CHEMBL327944 | N-Methyl-2,2-diphenyl-N-((1S,2S)-2-...) Show SMILES CN([C@H]1CCCC[C@@H]1N1CCCC1)C(=O)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H32N2O/c1-26(22-16-8-9-17-23(22)27-18-10-11-19-27)25(28)24(20-12-4-2-5-13-20)21-14-6-3-7-15-21/h2-7,12-15,22-24H,8-11,16-19H2,1H3/t22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferens				Bioorg Med Chem Lett 7: 291-296 (1997) Article DOI: 10.1016/S0960-894X(96)00615-4 BindingDB Entry DOI: 10.7270/Q2G160VS
					More data for this Ligand-Target Pair