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Found 1 hit Enz. Inhib. hit(s) with Target = 'Ketohexokinase' and Ligand = 'BDBM50380253'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ketohexokinase


(Homo sapiens (Human))		BDBM50380253
PNG
(CHEMBL2017222)
Show SMILES C(Nc1ncnc2c(Nc3ccccc3C3CC3)nc(nc12)N1CCNCC1)C1CC1
Show InChI InChI=1S/C23H28N8/c1-2-4-18(17(3-1)16-7-8-16)28-22-19-20(21(27-14-26-19)25-13-15-5-6-15)29-23(30-22)31-11-9-24-10-12-31/h1-4,14-16,24H,5-13H2,(H,25,26,27)(H,28,29,30)
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Article
PubMed
n/an/a 380n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human ketohexokinase isoform C expressed in Escherichia coli BL21 (DE3) cells using D-fructose as substrate after 12 to 15 mins by fluo...

ACS Med Chem Lett 2: 538-543 (2011)


Article DOI: 10.1021/ml200070g
BindingDB Entry DOI: 10.7270/Q2NZ88N1
More data for this
Ligand-Target Pair