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Found 1 hit Enz. Inhib. hit(s) with Target = 'Ketohexokinase' and Ligand = 'BDBM50380270'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ketohexokinase


(Homo sapiens (Human))		BDBM50380270
PNG
(CHEMBL2017237)
Show SMILES CN1CCN(CC1)c1nc(Nc2ccccc2C)c2ncnc(NCC3CC3)c2n1
Show InChI InChI=1S/C22H28N8/c1-15-5-3-4-6-17(15)26-21-18-19(20(25-14-24-18)23-13-16-7-8-16)27-22(28-21)30-11-9-29(2)10-12-30/h3-6,14,16H,7-13H2,1-2H3,(H,23,24,25)(H,26,27,28)
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PC cid
PC sid
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Similars
Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human ketohexokinase isoform C expressed in Escherichia coli BL21 (DE3) cells using D-fructose as substrate after 12 to 15 mins by fluo...

ACS Med Chem Lett 2: 538-543 (2011)


Article DOI: 10.1021/ml200070g
BindingDB Entry DOI: 10.7270/Q2NZ88N1
More data for this
Ligand-Target Pair