Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'KiSS-1 receptor' and Ligand = 'BDBM50196443'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
KiSS-1 receptor (Homo sapiens (Human))	BDBM50196443 (CHEMBL3939287) Show SMILES CNC(=N)NCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)NNC(=O)[C@H](Cc1cccc(F)c1)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@@H](Cc1ccc(O)cc1)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI InChI=1S/C55H75FN16O13/c1-28(2)20-40(50(81)66-38(14-9-19-61-54(59)60-5)49(80)67-39(47(58)78)24-33-26-62-37-13-7-6-12-36(33)37)69-55(85)72-71-52(83)42(23-32-10-8-11-34(56)21-32)68-53(84)46(29(3)73)70-51(82)43(25-44(57)76)65-45(77)27-63-48(79)41(64-30(4)74)22-31-15-17-35(75)18-16-31/h6-8,10-13,15-18,21,26,28-29,38-43,46,62,73,75H,9,14,19-20,22-25,27H2,1-5H3,(H2,57,76)(H2,58,78)(H,63,79)(H,64,74)(H,65,77)(H,66,81)(H,67,80)(H,68,84)(H,70,82)(H,71,83)(H3,59,60,61)(H2,69,72,85)/t29-,38+,39+,40+,41-,42+,43+,46+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Agonist activity at human KISS1R expressed in CHO/dhfr cells assessed as increase in intracellular Ca2+ levels measured for 180 secs by Fluo 3-AM dye...				J Med Chem 59: 8804-8811 (2016) Article DOI: 10.1021/acs.jmedchem.6b00379 BindingDB Entry DOI: 10.7270/Q2000425
					More data for this Ligand-Target Pair
KiSS-1 receptor (Rattus norvegicus)	BDBM50196443 (CHEMBL3939287) Show SMILES CNC(=N)NCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)NNC(=O)[C@H](Cc1cccc(F)c1)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@@H](Cc1ccc(O)cc1)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI InChI=1S/C55H75FN16O13/c1-28(2)20-40(50(81)66-38(14-9-19-61-54(59)60-5)49(80)67-39(47(58)78)24-33-26-62-37-13-7-6-12-36(33)37)69-55(85)72-71-52(83)42(23-32-10-8-11-34(56)21-32)68-53(84)46(29(3)73)70-51(82)43(25-44(57)76)65-45(77)27-63-48(79)41(64-30(4)74)22-31-15-17-35(75)18-16-31/h6-8,10-13,15-18,21,26,28-29,38-43,46,62,73,75H,9,14,19-20,22-25,27H2,1-5H3,(H2,57,76)(H2,58,78)(H,63,79)(H,64,74)(H,65,77)(H,66,81)(H,67,80)(H,68,84)(H,70,82)(H,71,83)(H3,59,60,61)(H2,69,72,85)/t29-,38+,39+,40+,41-,42+,43+,46+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.40	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Agonist activity at rat KISS1R expressed in CHO/dhfr cells assessed as increase in intracellular Ca2+ levels measured for 180 secs by Fluo 3-AM dye b...				J Med Chem 59: 8804-8811 (2016) Article DOI: 10.1021/acs.jmedchem.6b00379 BindingDB Entry DOI: 10.7270/Q2000425
					More data for this Ligand-Target Pair