Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'KiSS-1 receptor' and Ligand = 'BDBM50196483'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
KiSS-1 receptor (Rattus norvegicus)	BDBM50196483 (CHEMBL3958495) Show SMILES CNC(=N)NCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI InChI=1S/C58H80N16O15/c1-30(2)24-42(52(84)66-39(16-11-23-63-57(61)62-5)50(82)68-41(49(60)81)27-35-29-64-38-15-10-9-14-37(35)38)71-58(89)74-73-55(87)44(25-33-12-7-6-8-13-33)70-56(88)48(31(3)75)72-54(86)45(28-46(59)78)69-51(83)40(21-22-47(79)80)67-53(85)43(65-32(4)76)26-34-17-19-36(77)20-18-34/h6-10,12-15,17-20,29-31,39-45,48,64,75,77H,11,16,21-28H2,1-5H3,(H2,59,78)(H2,60,81)(H,65,76)(H,66,84)(H,67,85)(H,68,82)(H,69,83)(H,70,88)(H,72,86)(H,73,87)(H,79,80)(H3,61,62,63)(H2,71,74,89)/t31-,39+,40+,41+,42+,43-,44+,45+,48+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Agonist activity at rat KISS1R expressed in CHO/dhfr cells assessed as increase in intracellular Ca2+ levels measured for 180 secs by Fluo 3-AM dye b...				J Med Chem 59: 8804-8811 (2016) Article DOI: 10.1021/acs.jmedchem.6b00379 BindingDB Entry DOI: 10.7270/Q2000425
					More data for this Ligand-Target Pair
KiSS-1 receptor (Homo sapiens (Human))	BDBM50196483 (CHEMBL3958495) Show SMILES CNC(=N)NCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI InChI=1S/C58H80N16O15/c1-30(2)24-42(52(84)66-39(16-11-23-63-57(61)62-5)50(82)68-41(49(60)81)27-35-29-64-38-15-10-9-14-37(35)38)71-58(89)74-73-55(87)44(25-33-12-7-6-8-13-33)70-56(88)48(31(3)75)72-54(86)45(28-46(59)78)69-51(83)40(21-22-47(79)80)67-53(85)43(65-32(4)76)26-34-17-19-36(77)20-18-34/h6-10,12-15,17-20,29-31,39-45,48,64,75,77H,11,16,21-28H2,1-5H3,(H2,59,78)(H2,60,81)(H,65,76)(H,66,84)(H,67,85)(H,68,82)(H,69,83)(H,70,88)(H,72,86)(H,73,87)(H,79,80)(H3,61,62,63)(H2,71,74,89)/t31-,39+,40+,41+,42+,43-,44+,45+,48+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	2.80	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Agonist activity at human KISS1R expressed in CHO/dhfr cells assessed as increase in intracellular Ca2+ levels measured for 180 secs by Fluo 3-AM dye...				J Med Chem 59: 8804-8811 (2016) Article DOI: 10.1021/acs.jmedchem.6b00379 BindingDB Entry DOI: 10.7270/Q2000425
					More data for this Ligand-Target Pair