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Found 1 hit Enz. Inhib. hit(s) with Target = 'Kinesin-like protein 1' and Ligand = 'BDBM50068387'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein 1


(Homo sapiens (Human))
BDBM50068387
PNG
(CHEMBL3402348)
Show SMILES NCC(=O)N1N=C(SC11CCOc2ccccc12)c1cc(F)ccc1F |c:5|
Show InChI InChI=1/C18H15F2N3O2S/c19-11-5-6-14(20)12(9-11)17-22-23(16(24)10-21)18(26-17)7-8-25-15-4-2-1-3-13(15)18/h1-6,9H,7-8,10,21H2
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>1.00E+3n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of KSP in human HCT116 cells assessed as phos-histone H3 level by immunofluorescent assay


Bioorg Med Chem 23: 2424-34 (2015)


Article DOI: 10.1016/j.bmc.2015.03.052
More data for this
Ligand-Target Pair