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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kinesin-like protein 1' and Ligand = 'BDBM50382598'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein 1


(Homo sapiens (Human))
BDBM50382598
PNG
(CHEMBL2022992)
Show SMILES CC(=O)c1ccc(cc1)C(SCCN)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H23NOS/c1-18(25)19-12-14-22(15-13-19)23(26-17-16-24,20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2-15H,16-17,24H2,1H3
PDB
MMDB

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PC cid
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Article
PubMed
51n/an/an/an/an/an/an/an/a



The Beatson Institute for Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...


J Med Chem 55: 1511-25 (2012)


Article DOI: 10.1021/jm201195m
BindingDB Entry DOI: 10.7270/Q2CZ386T
More data for this
Ligand-Target Pair