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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kinesin-like protein KIFC1' and Ligand = 'BDBM50037887'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein KIFC1


(Homo sapiens (Human))
BDBM50037887
PNG
(CHEMBL3358267)
Show SMILES COCc1cc(ccc1OC)C(=O)NC(Cc1ccc(cc1)-c1cccc(c1)C(C)C)C(=O)NCCN(C)C
Show InChI InChI=1/C32H41N3O4/c1-22(2)25-8-7-9-26(19-25)24-12-10-23(11-13-24)18-29(32(37)33-16-17-35(3)4)34-31(36)27-14-15-30(39-6)28(20-27)21-38-5/h7-15,19-20,22,29H,16-18,21H2,1-6H3,(H,33,37)(H,34,36)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.10E+4n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal His6-tagged KIFC1 (Q305-K673 aa) (unknown origin) expressed in Escherichia coli BL21 (DE3) by malachite green as...


J Med Chem 57: 9958-70 (2014)


Article DOI: 10.1021/jm501179r
BindingDB Entry DOI: 10.7270/Q2QF8VG8
More data for this
Ligand-Target Pair