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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kinesin-like protein KIFC1' and Ligand = 'BDBM50037909'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein KIFC1


(Homo sapiens (Human))
BDBM50037909
PNG
(CHEMBL3358252)
Show SMILES CN(C)CCNC(=O)C(Cc1ccc(cc1)-c1cn2ccccc2n1)NC(=O)c1ccccc1OCc1ccccc1
Show InChI InChI=1/C34H35N5O3/c1-38(2)21-19-35-34(41)29(22-25-15-17-27(18-16-25)30-23-39-20-9-8-14-32(39)36-30)37-33(40)28-12-6-7-13-31(28)42-24-26-10-4-3-5-11-26/h3-18,20,23,29H,19,21-22,24H2,1-2H3,(H,35,41)(H,37,40)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal His6-tagged KIFC1 (Q305-K673 aa) (unknown origin) expressed in Escherichia coli BL21 (DE3) by malachite green as...


J Med Chem 57: 9958-70 (2014)


Article DOI: 10.1021/jm501179r
BindingDB Entry DOI: 10.7270/Q2QF8VG8
More data for this
Ligand-Target Pair