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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kinesin-like protein KIFC1' and Ligand = 'BDBM50037910'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein KIFC1


(Homo sapiens (Human))
BDBM50037910
PNG
(CHEMBL3358251)
Show SMILES OC(=O)[C@@H](Cc1ccc(cc1)-c1cccc(c1)C(F)(F)F)NC(=O)c1ccccc1OCc1ccccc1 |r|
Show InChI InChI=1/C30H24F3NO4/c31-30(32,33)24-10-6-9-23(18-24)22-15-13-20(14-16-22)17-26(29(36)37)34-28(35)25-11-4-5-12-27(25)38-19-21-7-2-1-3-8-21/h1-16,18,26H,17,19H2,(H,34,35)(H,36,37)/t26-/s2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.45E+4n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal His6-tagged KIFC1 (Q305-K673 aa) (unknown origin) expressed in Escherichia coli BL21 (DE3) by malachite green as...


J Med Chem 57: 9958-70 (2014)


Article DOI: 10.1021/jm501179r
BindingDB Entry DOI: 10.7270/Q2QF8VG8
More data for this
Ligand-Target Pair