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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kinesin-like protein KIFC1' and Ligand = 'BDBM50037960'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kinesin-like protein KIFC1


(Homo sapiens (Human))		BDBM50037960
PNG
(CHEMBL3358277)
Show SMILES CCCc1cc(sc1C)C(=O)N[C@@H](Cc1ccc(cc1)-c1cccc(c1)C(F)(F)F)C(=O)NCCN(C)C |r|
Show InChI InChI=1S/C29H34F3N3O2S/c1-5-7-22-18-26(38-19(22)2)28(37)34-25(27(36)33-14-15-35(3)4)16-20-10-12-21(13-11-20)23-8-6-9-24(17-23)29(30,31)32/h6,8-13,17-18,25H,5,7,14-16H2,1-4H3,(H,33,36)(H,34,37)/t25-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.50E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal His6-tagged KIFC1 (Q305-K673 aa) (unknown origin) expressed in Escherichia coli BL21 (DE3) by malachite green as...

J Med Chem 57: 9958-70 (2014)


Article DOI: 10.1021/jm501179r
BindingDB Entry DOI: 10.7270/Q2QF8VG8
More data for this
Ligand-Target Pair