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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kinesin-like protein KIFC1' and Ligand = 'BDBM50037963'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein KIFC1


(Homo sapiens (Human))
BDBM50037963
PNG
(CHEMBL3358274)
Show SMILES COCc1cc(ccc1OC)C(=O)N[C@H](Cc1ccc(cc1)-c1cccc(c1)C(F)(F)F)C(=O)NCCN(C)C |r|
Show InChI InChI=1/C30H34F3N3O4/c1-36(2)15-14-34-29(38)26(35-28(37)23-12-13-27(40-4)24(17-23)19-39-3)16-20-8-10-21(11-9-20)22-6-5-7-25(18-22)30(31,32)33/h5-13,17-18,26H,14-16,19H2,1-4H3,(H,34,38)(H,35,37)/t26-/s2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.60E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal His6-tagged KIFC1 (Q305-K673 aa) (unknown origin) expressed in Escherichia coli BL21 (DE3) by malachite green as...


J Med Chem 57: 9958-70 (2014)


Article DOI: 10.1021/jm501179r
BindingDB Entry DOI: 10.7270/Q2QF8VG8
More data for this
Ligand-Target Pair