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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kinesin-like protein KIFC1' and Ligand = 'BDBM50037969'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kinesin-like protein KIFC1


(Homo sapiens (Human))		BDBM50037969
PNG
(CHEMBL3358268)
Show SMILES COCc1cc(ccc1OC)C(=O)NC(Cc1ccc(cc1)-c1cccc(c1)C(C)(C)C)C(=O)NCCN(C)C
Show InChI InChI=1S/C33H43N3O4/c1-33(2,3)28-10-8-9-25(21-28)24-13-11-23(12-14-24)19-29(32(38)34-17-18-36(4)5)35-31(37)26-15-16-30(40-7)27(20-26)22-39-6/h8-16,20-21,29H,17-19,22H2,1-7H3,(H,34,38)(H,35,37)
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PC cid
PC sid
UniChem

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Similars
Article
PubMed
n/an/a 5.00E+4n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal His6-tagged KIFC1 (Q305-K673 aa) (unknown origin) expressed in Escherichia coli BL21 (DE3) by malachite green as...

J Med Chem 57: 9958-70 (2014)


Article DOI: 10.1021/jm501179r
BindingDB Entry DOI: 10.7270/Q2QF8VG8
More data for this
Ligand-Target Pair