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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kynurenine Aminotransferase 1/Glutamine Transaminase K' and Ligand = 'BDBM31881'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kynurenine Aminotransferase 1/Glutamine Transaminase K


(Homo sapiens (Human))
BDBM31881
PNG
(DL-indole-3-lactic acid)
Show SMILES OC(Cc1c[nH]c2ccccc12)C(O)=O
Show InChI InChI=1S/C11H11NO3/c13-10(11(14)15)5-7-6-12-9-4-2-1-3-8(7)9/h1-4,6,10,12-13H,5H2,(H,14,15)
PDB
MMDB

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PC cid
PC sid
PDB
UniChem

Patents

Article
PubMed
n/an/a 2.20E+5n/an/an/an/a7.538



Virginia Tech



Assay Description
A typical reaction mixture contains kynurenine, alpha-ketobutyrate, PLP and hKAT-I in the presence of test compound. The reaction mixture was incubat...


J Med Chem 52: 2786-93 (2009)


Article DOI: 10.1021/jm9000874
More data for this
Ligand-Target Pair