BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'L-lactate dehydrogenase A chain' and Ligand = 'BDBM50103569'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
L-lactate dehydrogenase A chain (Homo sapiens (Human))	BDBM50103569 (CHEMBL3335795) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	3.78E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute-CRO Curated by ChEMBL					Assay Description Competitive inhibition of human LDH5 incubated for 15 mins in presence of NADH by fluorescence analysis				J Med Chem 59: 487-96 (2016) Article DOI: 10.1021/acs.jmedchem.5b00168 BindingDB Entry DOI: 10.7270/Q2B27X41
National Cancer Institute-CRO Curated by ChEMBL					More data for this Ligand-Target Pair
L-lactate dehydrogenase A chain (Homo sapiens (Human))	BDBM50103569 (CHEMBL3335795) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	3.78E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of LDHA (unknown origin)				Bioorg Med Chem Lett 24: 4915-25 (2014) Article DOI: 10.1016/j.bmcl.2014.09.041 BindingDB Entry DOI: 10.7270/Q25Q4XV9
Universit£ di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair