Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'LIM domain kinase 2' and Ligand = 'BDBM50044015'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50044015 (CHEMBL3356421) Show SMILES CC(C)Oc1cccc(NC(=O)C2CCN(CC2)c2ncnc3[nH]cc(C)c23)c1 Show InChI InChI=1S/C22H27N5O2/c1-14(2)29-18-6-4-5-17(11-18)26-22(28)16-7-9-27(10-8-16)21-19-15(3)12-23-20(19)24-13-25-21/h4-6,11-14,16H,7-10H2,1-3H3,(H,26,28)(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...				ACS Med Chem Lett 6: 84-8 (2015) Article DOI: 10.1021/ml500367g BindingDB Entry DOI: 10.7270/Q218384X
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