Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'LIM domain kinase 2' and Ligand = 'BDBM50299609'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50299609 ((S)-N-(3-bromophenyl)-4-(2-chloro-7H-pyrrolo[2,3-d...) Show SMILES C[C@H]1CN(CCN1C(NC#N)=Nc1cccc(Br)c1)c1nc(Cl)nc2[nH]ccc12 |r,w:11.12| Show InChI InChI=1S/C19H18BrClN8/c1-12-10-28(17-15-5-6-23-16(15)26-18(21)27-17)7-8-29(12)19(24-11-22)25-14-4-2-3-13(20)9-14/h2-6,9,12H,7-8,10H2,1H3,(H,24,25)(H,23,26,27)/t12-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibition of human recombinant LIMK2 expressed in baculovirus-Sf9 system by scintillation counting				J Med Chem 52: 6515-8 (2009) Article DOI: 10.1021/jm901226j BindingDB Entry DOI: 10.7270/Q2HH6K4J
					More data for this Ligand-Target Pair