Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Lanosterol synthase' and Ligand = 'BDBM50133285'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lanosterol synthase (Homo sapiens (Human))	BDBM50133285 ((E)-3-Carboxy-acrylateallyl-{6-[4-(4-chloro-benzoy...) Show SMILES C[NH+](CCCCCCOc1ccc(C(=O)c2ccc(Cl)cc2)c(F)c1)CC=C Show InChI InChI=1S/C23H27ClFNO2/c1-3-14-26(2)15-6-4-5-7-16-28-20-12-13-21(22(25)17-20)23(27)18-8-10-19(24)11-9-18/h3,8-13,17H,1,4-7,14-16H2,2H3/p+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Tested for Oxidosqualene-lanosterol cyclase inhibition in T. brucei				J Med Chem 46: 4240-3 (2003) Article DOI: 10.1021/jm034126t BindingDB Entry DOI: 10.7270/Q26W99GV
					More data for this Ligand-Target Pair
Lanosterol synthase (Homo sapiens (Human))	BDBM50133285 ((E)-3-Carboxy-acrylateallyl-{6-[4-(4-chloro-benzoy...) Show SMILES C[NH+](CCCCCCOc1ccc(C(=O)c2ccc(Cl)cc2)c(F)c1)CC=C Show InChI InChI=1S/C23H27ClFNO2/c1-3-14-26(2)15-6-4-5-7-16-28-20-12-13-21(22(25)17-20)23(27)18-8-10-19(24)11-9-18/h3,8-13,17H,1,4-7,14-16H2,2H3/p+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Tested for Oxidosqualene-lanosterol cyclase inhibition in P. carinii				J Med Chem 46: 4240-3 (2003) Article DOI: 10.1021/jm034126t BindingDB Entry DOI: 10.7270/Q26W99GV
					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50133285 ((E)-3-Carboxy-acrylateallyl-{6-[4-(4-chloro-benzoy...) Show SMILES C[NH+](CCCCCCOc1ccc(C(=O)c2ccc(Cl)cc2)c(F)c1)CC=C Show InChI InChI=1S/C23H27ClFNO2/c1-3-14-26(2)15-6-4-5-7-16-28-20-12-13-21(22(25)17-20)23(27)18-8-10-19(24)11-9-18/h3,8-13,17H,1,4-7,14-16H2,2H3/p+1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Tested for Oxidosqualene-lanosterol cyclase inhibition in rat				J Med Chem 46: 4240-3 (2003) Article DOI: 10.1021/jm034126t BindingDB Entry DOI: 10.7270/Q26W99GV
					More data for this Ligand-Target Pair
Lanosterol synthase (Homo sapiens (Human))	BDBM50133285 ((E)-3-Carboxy-acrylateallyl-{6-[4-(4-chloro-benzoy...) Show SMILES C[NH+](CCCCCCOc1ccc(C(=O)c2ccc(Cl)cc2)c(F)c1)CC=C Show InChI InChI=1S/C23H27ClFNO2/c1-3-14-26(2)15-6-4-5-7-16-28-20-12-13-21(22(25)17-20)23(27)18-8-10-19(24)11-9-18/h3,8-13,17H,1,4-7,14-16H2,2H3/p+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Tested for Oxidosqualene-lanosterol cyclase inhibition in T. cruzi				J Med Chem 46: 4240-3 (2003) Article DOI: 10.1021/jm034126t BindingDB Entry DOI: 10.7270/Q26W99GV
					More data for this Ligand-Target Pair