BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Lanosterol synthase' and Ligand = 'BDBM50290992'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Lanosterol synthase (Rattus norvegicus)	BDBM50290992 (3-[16-(2,2-Difluoro-vinyl)-3,7,12,20-tetramethyl-h...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration that cause 50 percent inhibition of binding of [14C]-labeled (3S)-oxidosqualene to isolated rat liver oxidosqualene cyclase (OSC) was d...				Bioorg Med Chem Lett 7: 309-314 (1997) Article DOI: 10.1016/S0960-894X(97)00008-5 BindingDB Entry DOI: 10.7270/Q26H4HDR
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50290992 (3-[16-(2,2-Difluoro-vinyl)-3,7,12,20-tetramethyl-h...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration that cause 50 percent inhibition of binding of [14C]-labeled (3S)-oxidosqualene to isolated rat liver oxidosqualene cyclase (OSC) was d...				Bioorg Med Chem Lett 7: 309-314 (1997) Article DOI: 10.1016/S0960-894X(97)00008-5 BindingDB Entry DOI: 10.7270/Q26H4HDR
TBA Curated by ChEMBL					More data for this Ligand-Target Pair