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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2)' and Ligand = 'BDBM182708'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2)


(Homo sapiens (Human))
BDBM182708
PNG
(US9145402, 14)
Show SMILES CNc1nc(Nc2ccc(CN3CCOCC3)cc2OCCF)ncc1Cl
Show InChI InChI=1S/C18H23ClFN5O2/c1-21-17-14(19)11-22-18(24-17)23-15-3-2-13(10-16(15)27-7-4-20)12-25-5-8-26-9-6-25/h2-3,10-11H,4-9,12H2,1H3,(H2,21,22,23,24)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
9n/an/an/an/an/an/an/an/a



Genentech, Inc.

US Patent


Assay Description
his assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 38...


US Patent US9145402 (2015)


BindingDB Entry DOI: 10.7270/Q2J67FQ3
More data for this
Ligand-Target Pair