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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2)' and Ligand = 'BDBM60654'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2)


(Homo sapiens (Human))
BDBM60654
PNG
(US9145402, 3)
Show SMILES CNc1nc(Nc2cc(F)c(cc2OC)C#N)ncc1C(F)(F)F
Show InChI InChI=1S/C14H11F4N5O/c1-20-12-8(14(16,17)18)6-21-13(23-12)22-10-4-9(15)7(5-19)3-11(10)24-2/h3-4,6H,1-2H3,(H2,20,21,22,23)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
22n/an/an/an/an/an/an/an/a



Genentech, Inc.

US Patent


Assay Description
This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 3...


US Patent US9145402 (2015)


BindingDB Entry DOI: 10.7270/Q2J67FQ3
More data for this
Ligand-Target Pair