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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lipoprotein lipase' and Ligand = 'BDBM50444151'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lipoprotein lipase


(Homo sapiens (Human))
BDBM50444151
PNG
(CHEMBL3093306)
Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)Oc1ccc(Cl)nc1)C(F)(F)F |r|
Show InChI InChI=1S/C17H14ClF3N2O3/c18-15-4-2-11(8-22-15)26-12-5-6-23(9-12)14-3-1-10(17(19,20)21)7-13(14)16(24)25/h1-4,7-8,12H,5-6,9H2,(H,24,25)/t12-/m0/s1
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PC cid
PC sid
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Article
PubMed
n/an/a 3.16E+4n/an/an/an/an/an/a



Xenon Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...


Bioorg Med Chem 21: 7724-34 (2013)


Article DOI: 10.1016/j.bmc.2013.10.023
More data for this
Ligand-Target Pair