Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Low-density lipoprotein receptor-related protein 6' and Ligand = 'BDBM50145409'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Low-density lipoprotein receptor-related protein 6 (Homo sapiens (Human))	BDBM50145409 (CHEMBL3765394) Show SMILES COC(=O)c1c(NC2CCCC2)c(=O)c(O)c2oc3cc(ccc3nc12)N(C)C Show InChI InChI=1S/C21H23N3O5/c1-24(2)12-8-9-13-14(10-12)29-20-17(23-13)15(21(27)28-3)16(18(25)19(20)26)22-11-6-4-5-7-11/h8-11,22,26H,4-7H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Aristotle University of Thessaloniki Curated by ChEMBL					Assay Description Binding affinity to human LRP6 expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction using compound pre-treated DKK1 conditioned ...				Bioorg Med Chem 24: 1014-22 (2016) Article DOI: 10.1016/j.bmc.2016.01.025 BindingDB Entry DOI: 10.7270/Q2J67JRS
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