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Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 2B' and Ligand = 'BDBM319648'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific demethylase 2B


(Homo sapiens (Human))		BDBM319648
PNG
(2-{1-[(4-methoxyphenyl)methyl]-1H-imidazol-4-yl}- ...)
Show SMILES COc1ccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1
Show InChI InChI=1S/C19H15F3N6O/c1-29-14-4-2-12(3-5-14)9-28-10-16(24-11-28)15-8-13(6-7-23-15)17-18(19(20,21)22)26-27-25-17/h2-8,10-11H,9H2,1H3,(H,25,26,27)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



GSK



Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...

Bioorg Med Chem Lett 17: 1584-9 (2007)


BindingDB Entry DOI: 10.7270/Q2FT8PBQ
More data for this
Ligand-Target Pair