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Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 2B' and Ligand = 'BDBM319649'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific demethylase 2B


(Homo sapiens (Human))		BDBM319649
PNG
(2-{1-[(2,4-difluorophenyl)methyl]-1H-imidazol-4- y...)
Show SMILES Fc1ccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)c(F)c1
Show InChI InChI=1S/C18H11F5N6/c19-12-2-1-11(13(20)6-12)7-29-8-15(25-9-29)14-5-10(3-4-24-14)16-17(18(21,22)23)27-28-26-16/h1-6,8-9H,7H2,(H,26,27,28)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



GSK



Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...

Bioorg Med Chem Lett 17: 1584-9 (2007)


BindingDB Entry DOI: 10.7270/Q2FT8PBQ
More data for this
Ligand-Target Pair