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Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 2B' and Ligand = 'BDBM319674'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific demethylase 2B


(Homo sapiens (Human))		BDBM319674
PNG
(2-{1-[2-(4-methoxyphenyl)ethyl]-1H-imidazol-4-yl}-...)
Show SMILES COc1ccc(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)cc1
Show InChI InChI=1S/C20H17F3N6O/c1-30-15-4-2-13(3-5-15)7-9-29-11-17(25-12-29)16-10-14(6-8-24-16)18-19(20(21,22)23)27-28-26-18/h2-6,8,10-12H,7,9H2,1H3,(H,26,27,28)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



GSK



Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...

Bioorg Med Chem Lett 17: 1584-9 (2007)


BindingDB Entry DOI: 10.7270/Q2FT8PBQ
More data for this
Ligand-Target Pair