Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysine-specific demethylase 3A (Homo sapiens (Human)) | BDBM26113 (2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of KDM3A (unknown origin) expressed in Escherichia coli using H3 (1 to 21 residues) K9Me2-GGK-Biotin KDM3A Cognate Ligand/10 uM alpha-keto... | J Med Chem 59: 1580-98 (2016) Article DOI: 10.1021/acs.jmedchem.5b01527 BindingDB Entry DOI: 10.7270/Q2P84DRX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 3A (Homo sapiens (Human)) | BDBM26113 (2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Oxford | Assay Description The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was... | Nat Chem Biol 12: 539-45 (2016) Article DOI: 10.1038/nchembio.2087 BindingDB Entry DOI: 10.7270/Q27P8X6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 3A (Homo sapiens (Human)) | BDBM26113 (2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 7.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of KDM3A (unknown origin) | Medchemcomm 5: 1879-1886 (2014) Article DOI: 10.1039/C4MD00291A BindingDB Entry DOI: 10.7270/Q2KH0RBN | |||||||||||
More data for this Ligand-Target Pair |