Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 4C' and Ligand = 'BDBM270495'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM270495 (3-[({(1R)-6-[methyl(4-methyl-phenyl)amino]-1,2,3,4...) Show SMILES CN(c1ccc(C)cc1)c1ccc2[C@H](CNc3cnccc3C(O)=O)NCCc2c1 |r| Show InChI InChI=1S/C24H26N4O2/c1-16-3-5-18(6-4-16)28(2)19-7-8-20-17(13-19)9-12-26-23(20)15-27-22-14-25-11-10-21(22)24(29)30/h3-8,10-11,13-14,23,26-27H,9,12,15H2,1-2H3,(H,29,30)/t23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10059687 (2018) BindingDB Entry DOI: 10.7270/Q2TM7D54
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM270495 (3-[({(1R)-6-[methyl(4-methyl-phenyl)amino]-1,2,3,4...) Show SMILES CN(c1ccc(C)cc1)c1ccc2[C@H](CNc3cnccc3C(O)=O)NCCc2c1 |r| Show InChI InChI=1S/C24H26N4O2/c1-16-3-5-18(6-4-16)28(2)19-7-8-20-17(13-19)9-12-26-23(20)15-27-22-14-25-11-10-21(22)24(29)30/h3-8,10-11,13-14,23,26-27H,9,12,15H2,1-2H3,(H,29,30)/t23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2QV3RNH
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM270495 (3-[({(1R)-6-[methyl(4-methyl-phenyl)amino]-1,2,3,4...) Show SMILES CN(c1ccc(C)cc1)c1ccc2[C@H](CNc3cnccc3C(O)=O)NCCc2c1 |r| Show InChI InChI=1S/C24H26N4O2/c1-16-3-5-18(6-4-16)28(2)19-7-8-20-17(13-19)9-12-26-23(20)15-27-22-14-25-11-10-21(22)24(29)30/h3-8,10-11,13-14,23,26-27H,9,12,15H2,1-2H3,(H,29,30)/t23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description JMJD2C: The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditio...				US Patent US11001568 (2021) BindingDB Entry DOI: 10.7270/Q22V2K7S
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM270495 (3-[({(1R)-6-[methyl(4-methyl-phenyl)amino]-1,2,3,4...) Show SMILES CN(c1ccc(C)cc1)c1ccc2[C@H](CNc3cnccc3C(O)=O)NCCc2c1 |r| Show InChI InChI=1S/C24H26N4O2/c1-16-3-5-18(6-4-16)28(2)19-7-8-20-17(13-19)9-12-26-23(20)15-27-22-14-25-11-10-21(22)24(29)30/h3-8,10-11,13-14,23,26-27H,9,12,15H2,1-2H3,(H,29,30)/t23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description JMJD2C: The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditio...				US Patent US11001568 (2021) BindingDB Entry DOI: 10.7270/Q22V2K7S
					More data for this Ligand-Target Pair