Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 4C' and Ligand = 'BDBM50149921'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM50149921 (CHEMBL3769840) Show SMILES CC(C)n1cc(Oc2nc3cnccc3c(=O)[nH]2)cn1 Show InChI InChI=1S/C22H22BrN5O6S2/c1-35(31,32)28-18(22(30)27-20-11-10-16(23)12-25-20)13-26-21(29)15-8-6-14(7-9-15)17-4-2-3-5-19(17)36(24,33)34/h2-12,18,28H,13H2,1H3,(H,26,29)(H2,24,33,34)(H,25,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of N-terminal his-tagged human KDM4C expressed in Escherichia coli BL21(DE3) using trimethylated peptide substrate by RFMS assay				J Med Chem 59: 1370-87 (2016) Article DOI: 10.1021/acs.jmedchem.5b01538 BindingDB Entry DOI: 10.7270/Q26D5VV2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM50149921 (CHEMBL3769840) Show SMILES CC(C)n1cc(Oc2nc3cnccc3c(=O)[nH]2)cn1 Show InChI InChI=1S/C22H22BrN5O6S2/c1-35(31,32)28-18(22(30)27-20-11-10-16(23)12-25-20)13-26-21(29)15-8-6-14(7-9-15)17-4-2-3-5-19(17)36(24,33)34/h2-12,18,28H,13H2,1H3,(H,26,29)(H2,24,33,34)(H,25,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of N-terminal his-tagged full-length human KDM4C transfected in U2OS cells assessed as inhibition of H3K9Me3 demethylation for 24 hrs				J Med Chem 59: 1370-87 (2016) Article DOI: 10.1021/acs.jmedchem.5b01538 BindingDB Entry DOI: 10.7270/Q26D5VV2
					More data for this Ligand-Target Pair