Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysine-specific demethylase 5B (Homo sapiens (Human)) | BDBM270507 (3-[({(1R)-5-[2-methyl-4-(2,2,2-trifluoroethoxy)phe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc. US Patent | Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8... | US Patent US10059687 (2018) BindingDB Entry DOI: 10.7270/Q2TM7D54 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 5B (Homo sapiens (Human)) | BDBM270507 (3-[({(1R)-5-[2-methyl-4-(2,2,2-trifluoroethoxy)phe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2QV3RNH | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 5B (Homo sapiens (Human)) | BDBM270507 (3-[({(1R)-5-[2-methyl-4-(2,2,2-trifluoroethoxy)phe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
CELGENE QUANTICEL RESEARCH, INC. US Patent | Assay Description Jarid1b: The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction condit... | US Patent US11001568 (2021) BindingDB Entry DOI: 10.7270/Q22V2K7S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 5B (Homo sapiens (Human)) | BDBM270507 (3-[({(1R)-5-[2-methyl-4-(2,2,2-trifluoroethoxy)phe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
CELGENE QUANTICEL RESEARCH, INC. US Patent | Assay Description Jarid1b: The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction condit... | US Patent US11001568 (2021) BindingDB Entry DOI: 10.7270/Q22V2K7S | |||||||||||
More data for this Ligand-Target Pair |