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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 5B' and Ligand = 'BDBM277775'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM277775
PNG
(N-cyano-3-({1-[2-(3,3-difluoropyrrolidin-1yl)ethyl...)
Show SMILES Fc1ccc2n(CCN3CCC(F)(F)C3)nc(Nc3cnccc3C(=O)NC#N)c2c1
Show InChI InChI=1S/C20H18F3N7O/c21-13-1-2-17-15(9-13)18(27-16-10-25-5-3-14(16)19(31)26-12-24)28-30(17)8-7-29-6-4-20(22,23)11-29/h1-3,5,9-10H,4,6-8,11H2,(H,26,31)(H,27,28)
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Celgene Quanticel Research Inc

US Patent


Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...

US Patent US10336727 (2019)


BindingDB Entry DOI: 10.7270/Q2571FBT
More data for this
Ligand-Target Pair