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Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 5B' and Ligand = 'BDBM319638'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM319638
PNG
(2-{1-[2-(2-chlorophenyl)ethyl]-1H-imidazol-4-yl}-4...)
Show SMILES FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2ccccc2Cl)cn1
Show InChI InChI=1S/C19H14ClF3N6/c20-14-4-2-1-3-12(14)6-8-29-10-16(25-11-29)15-9-13(5-7-24-15)17-18(19(21,22)23)27-28-26-17/h1-5,7,9-11H,6,8H2,(H,26,27,28)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



GSK



Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...

Bioorg Med Chem Lett 17: 1584-9 (2007)


BindingDB Entry DOI: 10.7270/Q2FT8PBQ
More data for this
Ligand-Target Pair