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Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 5B' and Ligand = 'BDBM319667'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific demethylase 5B


(Homo sapiens (Human))		BDBM319667
PNG
(2-{1-[2-(2,4-difluorophenyl)ethyl]-1H-imidazol-4- ...)
Show SMILES Fc1ccc(CCn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C(F)(F)F)c(F)c1
Show InChI InChI=1S/C19H13F5N6/c20-13-2-1-11(14(21)8-13)4-6-30-9-16(26-10-30)15-7-12(3-5-25-15)17-18(19(22,23)24)28-29-27-17/h1-3,5,7-10H,4,6H2,(H,27,28,29)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



GSK



Assay Description
The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...

Bioorg Med Chem Lett 17: 1584-9 (2007)


BindingDB Entry DOI: 10.7270/Q2FT8PBQ
More data for this
Ligand-Target Pair