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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 5C' and Ligand = 'BDBM50153179'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 5C


(Homo sapiens (Human))
BDBM50153179
PNG
(CHEMBL3775933)
Show SMILES OC(=O)c1ccnc(c1)-c1cscn1
Show InChI InChI=1S/C9H6N2O2S/c12-9(13)6-1-2-10-7(3-6)8-4-14-5-11-8/h1-5H,(H,12,13)
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 122n/an/an/an/an/an/a



The Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...


J Med Chem 59: 1388-409 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01635
BindingDB Entry DOI: 10.7270/Q2W097TR
More data for this
Ligand-Target Pair