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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 6B' and Ligand = 'BDBM50140344'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 6B


(Homo sapiens (Human))
BDBM50140344
PNG
(CHEMBL3753122)
Show SMILES COc1ccccc1N1CCN(CC1)c1cc(nc(NCCC(O)=O)n1)-n1nccn1
Show InChI InChI=1S/C20H24N8O3/c1-31-16-5-3-2-4-15(16)26-10-12-27(13-11-26)17-14-18(28-22-8-9-23-28)25-20(24-17)21-7-6-19(29)30/h2-5,8-9,14H,6-7,10-13H2,1H3,(H,29,30)(H,21,24,25)
PDB

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CHEMBL
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay


Bioorg Med Chem Lett 26: 721-5 (2016)


BindingDB Entry DOI: 10.7270/Q2P55QC2
More data for this
Ligand-Target Pair