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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 6B' and Ligand = 'BDBM50140349'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 6B


(Homo sapiens (Human))
BDBM50140349
PNG
(CHEMBL3754555)
Show SMILES OC(=O)CCNc1nc(cc(n1)-n1cc2ccccc2n1)N1CCc2ccccc2CC1
Show InChI InChI=1S/C24H24N6O2/c31-23(32)9-12-25-24-26-21(29-13-10-17-5-1-2-6-18(17)11-14-29)15-22(27-24)30-16-19-7-3-4-8-20(19)28-30/h1-8,15-16H,9-14H2,(H,31,32)(H,25,26,27)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 2.20E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay


Bioorg Med Chem Lett 26: 721-5 (2016)


BindingDB Entry DOI: 10.7270/Q2P55QC2
More data for this
Ligand-Target Pair