Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM301072'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301072 (4-[2-(2,3,3a,4,5,7,8,8a-octahydro-1H- pyrrolo[3,4-...) Show SMILES Cn1ncc2cc(cnc12)-c1cnc(nc1-c1ccc(cc1)C#N)N1CCC2CNCC2CC1 Show InChI InChI=1S/C26H26N8/c1-33-25-22(15-31-33)10-21(14-29-25)23-16-30-26(32-24(23)18-4-2-17(11-27)3-5-18)34-8-6-19-12-28-13-20(19)7-9-34/h2-5,10,14-16,19-20,28H,6-9,12-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
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