Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM301081'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301081 (4-[2-(4-aminopiperidin-1-yl)-5-(2- methoxypyrimidi...) Show SMILES COc1ncc(cn1)-c1cnc(nc1-c1ccc(cc1)C#N)N1CCC(N)CC1 Show InChI InChI=1S/C21H21N7O/c1-29-21-25-11-16(12-26-21)18-13-24-20(28-8-6-17(23)7-9-28)27-19(18)15-4-2-14(10-22)3-5-15/h2-5,11-13,17H,6-9,23H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair